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Jean-Charles Deybach Selected Research

Heme (Haem)

5/2024From chemistry to genomics: A concise history of the porphyrias.
1/2020EXPLORE: A Prospective, Multinational, Natural History Study of Patients with Acute Hepatic Porphyria with Recurrent Attacks.
11/2019Hepatocellular carcinoma in acute hepatic porphyrias: A Damocles Sword.
1/2019Current and innovative emerging therapies for porphyrias with hepatic involvement.
1/2018From a dominant to an oligogenic model of inheritance with environmental modifiers in acute intermittent porphyria.
9/2015Porphyrias: A 2015 update.
9/2015Mitochondrial energetic defects in muscle and brain of a Hmbs-/- mouse model of acute intermittent porphyria.
8/2015High prevalence of and potential mechanisms for chronic kidney disease in patients with acute intermittent porphyria.
1/2015Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites.
6/2014Acute intermittent porphyria causes hepatic mitochondrial energetic failure in a mouse model.
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Jean-Charles Deybach Research Topics

Disease

12Porphyrias (Porphyria)
05/2024 - 01/2002
10Erythropoietic Protoporphyria
01/2019 - 01/2002
9Acute Intermittent Porphyria (Porphyria, Acute)
05/2024 - 01/2002
4Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency)
11/2019 - 01/2002
3Inborn Genetic Diseases (Disease, Hereditary)
01/2020 - 08/2015
3Hepatic Porphyrias (Hepatic Porphyria)
11/2019 - 01/2002
3Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)
11/2019 - 02/2002
3Erythropoietic Porphyria (Congenital Erythropoietic Porphyria)
08/2011 - 02/2004
2Metabolic Diseases (Metabolic Disease)
01/2019 - 09/2015
2Hemochromatosis (Bronze Diabetes)
12/2013 - 02/2007
2Liver Failure
10/2011 - 09/2009
2X-linked sideroblastic anemia
06/2011 - 09/2008
2Schizophrenia (Dementia Praecox)
04/2010 - 03/2004
2Liver Diseases (Liver Disease)
09/2009 - 09/2008
1Pain (Aches)
07/2015
1Carcinoma (Carcinomatosis)
09/2013
1Melanoma (Melanoma, Malignant)
04/2013
1Erythema
04/2013
1Phototoxic Dermatitis (Phototoxicity)
04/2013
1Hepatocellular Carcinoma (Hepatoma)
01/2012
1Sclerosing Cholangitis
10/2011
1Cholestasis
10/2011
1Digestive System Diseases
10/2011
1Fibrosis (Cirrhosis)
10/2011
1Sideroblastic Anemia
06/2011
1Acute Liver Failure (Fulminant Hepatic Failure)
09/2009
1Cholelithiasis
09/2009
1Iron-Deficiency Anemia (Anemia, Iron Deficiency)
01/2007
1Hypochromic Anemia (Chlorosis)
01/2007
1Iron Deficiencies
01/2007
1Thrombophilia
06/2003
1Alcoholism (Alcohol Abuse)
11/2002
1Porphyria Cutanea Tarda
01/2002

Drug/Important Bio-Agent (IBA)

19Heme (Haem)IBA
05/2024 - 01/2002
8EnzymesIBA
01/2019 - 07/2004
8Ferrochelatase (Heme Synthetase)IBA
01/2019 - 01/2002
7Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA
11/2019 - 01/2002
5PorphyrinsIBA
05/2024 - 01/2002
5protoporphyrin IXIBA
10/2011 - 06/2005
4Protoporphyrinogen Oxidase (Protox)IBA
11/2019 - 02/2002
3Aminolevulinic Acid (Levulan)FDA Link
05/2024 - 08/2015
3PorphobilinogenIBA
05/2024 - 08/2015
3Acute Hepatic PorphyriaIBA
01/2020 - 10/2005
3Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)IBA
11/2019 - 01/2002
3IronIBA
06/2011 - 01/2007
3Dopamine Receptors (Dopamine Receptor)IBA
04/2010 - 11/2002
2Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2007
2Messenger RNA (mRNA)IBA
01/2019 - 01/2007
2Hemochromatosis ProteinIBA
12/2013 - 02/2007
1Hydro-Lyases (Dehydratases)IBA
05/2024
1Dioctyl Sulfosuccinic Acid (DOSS)IBA
05/2024
1LigandsIBA
01/2019
1Peptides (Polypeptides)IBA
01/2019
1afamelanotideIBA
07/2015
1Melanocyte-Stimulating Hormones (MSH)IBA
07/2015
1Antisense OligonucleotidesIBA
04/2014
1VemurafenibIBA
04/2013
1Blood Group Antigens (Blood Groups)IBA
01/2012
1Bile Acids and Salts (Bile Acids)IBA
10/2011
1Indicators and Reagents (Reagents)IBA
10/2011
1Uroporphyrinogen III Synthetase (Uroporphyrinogen-III Synthase)IBA
08/2011
15-Aminolevulinate SynthetaseIBA
08/2011
1zinc protoporphyrinIBA
09/2008
1Ceruloplasmin (Ferroxidase)IBA
02/2007
1Transferrin Receptors (Transferrin Receptor)IBA
01/2007
1Transferrin (beta 2 Transferrin)IBA
01/2007
1Oxidoreductases (Dehydrogenase)IBA
10/2005
1coproporphyrinogen IIIIBA
10/2005
1Phosphotransferases (Kinase)IBA
03/2004
1Factor V (Coagulation Factor V)IBA
06/2003
1Dopamine (Intropin)FDA LinkGeneric
11/2002
1Estrogens (Estrogen)FDA Link
01/2002

Therapy/Procedure

5Therapeutics
01/2019 - 02/2005
2Liver Transplantation
10/2011 - 07/2004
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
02/2005
1Stem Cell Transplantation
02/2005